Ribozyme-related publications.

 

Smith, M.D. and Collins, R.A. (2011). Use of ribozyme cleavage kinetics to measure salt-induced  changes in solution pH. Anal. Biochem. 415: 12-20. ScienceDirect

 

DeAbeu, D.M., Olive, J. and Collins, R.A. (2011). Additional roles of a peripheral loop-loop interaction in the Neurospora VS ribozyme. Nucl. Acids Res. 39: 6223-6228. PubMed

 

Smith, M.D., Mehdizadeh, R. Olive, J.E and Collins, R.A. (2008). The ionic environment determines ribozyme cleavage rate by modulation of nucleobase pKa. RNA 14: 1942-1949. PubMed

 

Pereira, M.J.B., Nikolova, E.N. Hiley, S.L., Jaikaran, D.J., Collins, R.A. and Walter, N.G. (2008). Single molecule FRET microscopy of a complex ribozyme reveals dynamic concerted folding toward catalysis. J. Mol. Biol. 382: 496-509. PubMed

 

Jaikaran, D.J., Smith, M.D., Mehdizadeh, R., Olive, J.E. and Collins, R.A. (2008).  An important role of G638 in the cis-cleavage reaction of the Neurospora VS ribozyme revealed by a novel nucleotide analog incorporation method.  RNA 14: 938-949. PubMed

 

Smith, M.D. and Collins, R.A. (2007). Evidence for proton transfer in the rate-limiting step of fast-cleaving Neurospora VS ribozymes.  Proc. Nat. Acad. Sci., 104: 5818-5823. PubMed

 

Poon, A. Olive, J.E., McLaren, M. and Collins, R.A. (2006). Separate structural features determine the cleavage rate and cation optimum of the self-cleavage reaction of the Neurospora VS ribozyme. Biochemistry 45: 13394-13400. Biochemistry

 

Zamel, R., Poon, A. Jaikaran, D. Andersen, A., Olive, J.E., DeAbreu, D.M. and Collins, R.A. (2004). Exceptionally fast self-cleavage by a Neurospora VS ribozyme. Proc. Nat. Acad. Sci. 101: 1467-1472. PubMed

 

Hoffmann, B., Mitchell, G.T., Andersen, A.A., Collins, R.A., and Legault, P. (2003). NMR structure of the active cleavage site of the Neurospora VS ribozyme. Proc. Nat. Acad. Sci 100: 7003-7008. PubMed

 

Collins, R.A. (2002). The Neurospora Varkud satellite ribozyme. Biochem Soc Transactions 30(6): 1122-1126. PortlandPress

 

Zamel, R. and Collins, R.A. (2002). Rearrangement of substrate secondary structure facilitates binding to the  Neurospora VS ribozyme. J. Mol. Biol. 324: 903-915. ScienceDirect

 

Hiley, S. Sood, V., Fan, J. and Collins, R.A. (2002) 4-thio-U crosslinking identifies the active site of the VS ribozyme. EMBO J. 17:  4691-4698. PubMed

 

Sood, V.D. and Collins, R.A. (2002). Identification of the catalytic subdomain of the Neurospora VS ribozyme and evidence for remarkable sequence tolerance in the active site loop. J. Mol. Biol. 329: 443-454. ScienceDirect

 

Sood, V.D. Yekta, S.and Collins, R.A. (2002). The contribution of 2’-hydroxyls to the cleavage activity of the Neurospora VS ribozyme. Nucl. Acids Res. 30: 1132-1138. PubMed

 

Sood, V.D. and Collins, R.A. (2001). Functional equivalence of the uridine turn and the hairpin as building blocks of Neurospora VS ribozyme structure. J. Mol. Biol. 313: 1013-1019. ScienceDirect

 

Hiley, S. and Collins, R.A. (2001). Rapid formation of a solvent-inaccessible core in the Neurospora VS ribozyme. EMBO J. 20: 5461-5469. PubMed

 

Andersen, A. and Collins, R.A. (2001). Intramolecular base pair rearrangement by the kissing interaction of the Neurospora VS ribozyme. Proc. Nat. Acad. Sci. 98 7730-7735. PubMed

 

Maguire, J.L. and Collins, R.A. (2001). Effects of cobalt hexammine on folding and self-cleavage of the Neurospora VS ribozyme, J. Mol. Biol. 309: 45-56. ScienceDirect

 

Andersen, A. and Collins, R.A. (2000). Rearrangement of a stable RNA secondary structure during VS ribozyme catalysis. Molecular Cell 5: 469-478. ScienceDirect

 

Sood, V.D., Beattie, T.L. and Collins, R.A. (1998). Identification of phosphates involved in metal binding and tertiary folding in the core of the Neurospora VS ribozyme.  J. Mol. Biol. 282:741-750. ScienceDirect

 

Olive, J.E. and Collins, R.A. (1998) Spermine switches a Neurospora VS ribozyme from slow cis-cleavage to fast trans-cleavage.  Biochemistry 37: 6476-6484. Biochemistry

 

Rastogi, T. and Collins, R.A. (1998). Smaller, faster VS ribozymes identify the catalytic core of the Neurospora VS ribozyme.  J. Mol. Biol. 277: 215-224. ScienceDirect

 

Beattie, T.L. and Collins, (1997). Identification of functional domains in the self-cleaving Neurospora VS ribozyme using damage selection.  J. Mol. Biol. 267: 830-840. ScienceDirect

 

Rastogi, T.R., Beattie, T.L., Olive, J.E. and Collins, R.A. (1996). A long-range pseudoknot is required for activity of the Neurospora VS ribozyme.  EMBO J. 15: 2820-2825. PubMed

 

Olive, J.E., De Abreu, D.M., Rastogi, T., Andersen, A.A., Mittermaier, A.K., Beattie, T.L. and Collins, R.A. (1995). Enhancement of Neurospora VS ribozyme cleavage by tuberactinomycin antibiotics. EMBO J. 14: 3247-3251. PubMed

 

Beattie, T., Olive, J.E. and Collins, R.A. (1995). A secondary structure model for the self-cleaving region of Neurospora VS RNA.  Proc. Nat. Acad. Sci. 92, 4686-4690. PubMed

 

Kennell, J.C., Saville, B.J., Mohr, S., Kuiper, M.T.R., Sabourin, J.R. Collins, R.A. and Lambowitz, A.M. (1995). The VS catalytic RNA replicates by reverse transcription as a satellite of a retroplasmid.  Genes and Development 9, 294-303. Genes & Dev

 

Guo, H.C.T. and Collins, R.A. (1995).  Efficient trans-cleavage of a stem-loop substrate RNA by a ribozyme derived from Neurospora VS RNA.  EMBO J. 14: 368-378. PubMed

 

Guo, H.C-T., De Abreu, D.M., Tillier, E.R.M., Saville, B.J., Olive, J.E. and Collins, R.A. (1993).  Nucleotide sequence requirements for self-cleavage of Neurospora VS RNA.  J. Mol. Biol. 232: 351-361. ScienceDirect

 

Collins, R.A. and Olive, J.E. (1993).  Reaction conditions and kinetics of self-cleavage of a ribozyme derived from Neurospora VS RNA.  Biochemistry 32: 2795-2799. Biochemistry

 

Saville, B.J. and Collins, R.A. (1991). RNA-mediated ligation of self-cleavage products of a Neurospora mitochondrial plasmid transcript.  Proc. Nat Acad. Sci. 88: 8826-8830. PubMed

 

Saville, B.J. and Collins, R.A.  (1990). A site-specific self-cleavage reaction performed by a novel RNA in Neurospora mitochondria.  Cell 61: 685-696. ScienceDirect