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[null,"HEARING LOSS CALCULATOR IN CHILDREN"]
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[null,"This calculator estimates the risk of severe hearing loss (requiring hearing aids) after radiation treatment, with or without chemotherapy, for central nervous system (CNS) or head-and-neck tumours in children."]
[null,"Enter patient and treatment details in the boxes below to calculate estimated risk (%) of SIOP-Boston grade 3-4 hearing loss."]
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[null,null,"Patient details","Variables","Constants","Term"]
[]
[null,"Intercept",null,null,-4.0434,{"$f":"E10","v":-4.0434}]
[]
[null,"Age less than 3 years","N",{"$f":"IF(C12=\"Y\",1,0)","v":0},0.8726,{"$f":"E12*D12","v":0}]
[null,"Time since RT (years)",3,{"$f":"C13","v":3},0.1984,{"$f":"E13*D13","v":0.5952}]
[null,"Cisplatin (mg/m2)",300,{"$f":"C14/100","v":3},0.1148,{"$f":"E14*D14","v":0.3444}]
[null,"Carboplatin (mg/m2)",0,{"$f":"C15/1000","v":0},0.2849,{"$f":"E15*D15","v":0}]
[null,"Mean cochlea dose (Gy)",40,{"$f":"C16","v":40},0.0476,1.9040000000000001]
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[{"$nulls":4},"Sum of terms",{"$f":"SUM(F10:F16)","v":-1.1998}]
[]
[null,"Estimated risk of severe hearing loss",{"$nulls":5},{"$f":"1/(1+EXP(-F18))","v":{"v":0.23151079729985838,"d":"23%"}}]
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[null,"To learn more about the SIOP-Boston ototoxicity scale:"]
[null,"https://doi.org/10.1200/JCO.2011.39.1110"]
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[null,"By Derek S. Tsang, Sameera Ahmed et al."]
[null,"Version 1.1"]
{"$rows_empty":9}
[null,"Y"]
[null,"N"]