Our lab is located in modern, open-concept laboratory space on the 16th floor of the stunning MaRS Centre West Tower in downtown Toronto, alongside an assemblage of infectious disease researchers from the Departments of Molecular Genetics and Biochemisty. Our group is interested in the evolution of microbial pathogens and the molecular mechanisms by which these diminutive organisms persist in our environment and make us sick.
We focus our attention on Legionella pneumophila, a remarkable bacterial pathogen that maintains the microbial world's largest known arsenal of translocated effectors (with over 300 identified to date). Unlocking the secrets of this arsenal holds immense promise to provide novel insight into fundamental eukaryotic pathways, human health, and disease.
(Click here for the #upgoerfive inspired description of our research).