This is a first version of the GEE program for estimating the locations and mean ASP IBD sharing of two linked disease genes (Biernacka et al, 2005, Genetic Epidemiology, in press). It is an extension of the method proposed by Liang et al (2001, Human Heredity 51: 64-78) for localizing a single disease gene in a region. (The program for localizing a single disease gene in a region, GENEFINDER, is available here.)
Note that: I wrote this program under UNIX and compiled it with the F77 fortran compiler. Some modifications may need to be made in order to compile the program in different environments or with other compilers.
I know that there is room for improvement, and will try to update the files as soon as I get a chance to work on it. If you have any questions/comments or suggestions for improving the programs or documentation please let me know (email: biernac(at)fisher.utstat.utoronto.ca).
Thank you,
Joanna
README file.
Documentation and Instructions: documentation.GEE2loc.fit
Fortran Code: GEE2loc.fit.r1.f
SAS program to generate input files from Genehunter output: fileprep.sas