CHL5918H - BIOLOGICAL HAZARDS IN THE WORKPLACE AND COMMUNITY

COURSE DIRECTOR: Dr. James Scott, Dalla Lana School of Public Health, University of Toronto
OFFICE: Gage Bldg Rm 118, 223 College St
TEL: +1 416 946 8778
EMAIL: james.scott@utoronto.ca

COURSE DESCRIPTION:
This course is intended to familiarize students with a wide range of biological hazards that may be encountered in community- and work environments, including commercial, non-industrial, industrial and health care settings, with emphasis on the methods occupational hygienists use to recognize, evaluate and control microbiological hazards. Course modules include: 1) bioaerosol science & sampling; 2) microbiology of the built environment; 3) investigation, sampling, interpretation & remediation of indoor microbial contamination; 4) laboratory biosafety; 5) health care biosafety; 6) industrial biosafety; and 7) biological weapons. Readings will be taken from texts and primary literature.

SCHEDULE AND TIMING:
The course will meet weekly M9-12 in Gage Bldg classroom. Sessions will be in lecture format. Click here to download the course syllabus.

READINGS:
I expect that you will complete each weeks reading prior to the lecture. I will try to provide readings as handouts or pdfs. Readings for this course will be taken from several texts, including:

  • Adan O, Samson RA (eds). 2011. Fundamentals of mold growth in indoor environments and strategies for healthy living. Wageningen: Wageningen Academic Publishers, The Netherlands.
  • Flannigan B, Samson RA, Miller JD (eds). 2011. Microorganisms in home and indoor work environments: diversity, health impacts, investigation and control, 2nd ed. Boca Raton, FL: CRC Press, 529 pp.
  • Prezant B, Weekes DM, Miller JD. 2008. Recognition, evaluation and control of indoor mold. Fairfax Virginia: AIHA Press, 253 pp.
  • Zajtchuk R, Bellamy RF (eds). 1997. Medical aspects of chemical and biological warfare, Washington DC: Borden Institute.


2017 LECTURE SCHEDULE:


DATE MODULE 1: MICROBES IN IAQ
Jan 9, 2017 Review of microbiology - viruses and bacteria
Readings: Scott, J.A., Summerbell, R.C. & Green, B.J. 2011. Detection of indoor bioaerosols. Chapter 13. In: Adan, O. & Samson, R.A. Fundamentals of mold growth in indoor environments and strategies for healthy living. Wageningen: Wageningen Academic Publishers. pp 353-379.

Jan 16, 2017 Review of microbiology - eukaryotes
Readings: Flannigan B. 2011. Microorganisms in indoor air. Chapter 1.2. In: Flannigan B, Samson RA, Miller JD (eds). 2011. Microorganisms in home and indoor work environments: diversity, health impacts, investigation and control, 2nd ed. Boca Raton, FL: CRC Press. pp 3-43; Gomez-Valeroa L, Rusnioka C, Buchrieser C. 2009. Legionella pneumophila population genetics, phylogeny and genomics. Genetics and Evolution 9: 727-739.

Jan 23, 2017 Exposure hazards and pathways, bioaerosols & sampling
Reading: Prezant B, Weekes DM, Miller JD. 2008. Recognition, evaluation and control of indoor mold. Fairfax VA: AIHA Press. Chapters 10-12 (pp. 129-170).

Jan 30, 2017 Analytical methods
Reading: Flannigan B, Miller JD. 2011. Microbial growth in indoor environments. Chapter 2.1. In: Flannigan B, Samson RA, Miller JD (eds). 2011. Microorganisms in home and indoor work environments: diversity, health impacts, investigation and control, 2nd ed. Boca Raton, FL: CRC Press. pp 57-107.; Malloch DW. 1981. Moulds: Their isolation, cultivation and identification, Toronto: University of Toronto Press, Chapters 1 & 3.

Feb 6, 2017 Microbes in the built environment
Reading: Prezant B, Weekes DM, Miller JD. 2008. Recognition, evaluation and control of indoor mold. Fairfax VA: AIHA Press. Chapters 5-7 (pp. 55-96).

Feb 13, 2017 Mould remediation
Reading: Prezant B, Weekes DM, Miller JD. 2008. Recognition, evaluation and control of indoor mold. Fairfax VA: AIHA Press. Chapters 14-17 (pp. 179-213).

DATE MODULE 2: BIOSAFETY & BIOSECURITY
Feb 27, 2017 Biosafety principles
Reading: Public Health Agency of Canada (PHAC). 2015. Canadian Biosafety Standard. PHAC Ottawa, Chapters 1-2.

Mar 6, 2017 Biosafety risk assessment
Reading: Public Health Agency of Canada (PHAC). 2015. Canadian Biosafety Standard. PHAC Ottawa, Chapters 3-5.

Mar 13, 2017 Laboratory biosafety
Readings: Kruse RH, Puckett WH, Richardson JH. 1991. Biological safety cabinetry. Clinical Microbiology Reviews 4(2): 207-241; Singh K. 2009. Laboratory-acquired infections. Clinical INfectious Diseases 49: 142-147; Wurtz N, Papa A, Hukie M et al. 2016. Survey of laboratory-acquired infections around the world in biosafety level 3 and 4 laboratories. European Journal of Clinical Infectious Disease 35: 1247-1258.

Mar 20, 2017 Industrial biosafety
Readings: TBA.

Mar 27, 2017 Biosafety in health care
Readings: Mayhall CG (ed). 2004. Hospital epidemiology and infection control, 3rd edition. Lippincott Williams & Wilkins, Philadelphia PA. Chapters 3, 4 & 35; Tellier R. 2006. Review of aerosol transmission of influenza A virus. Emerging Infectious Diseases.

Apr 3, 2017 Dual use agents
Readings: Zajtchuk R, Bellamy RF (eds). 1997. Medical aspects of chemical and biological warfare, Washington DC: Borden Institute, Chapters 2, 19 and 21.

Apr 10, 2017 FINAL EXAMINATION

EVALUATION:

  • Assignment #1 will consist of a 5,000 word mock book chapter for a book on workplace biological hazards. You will sign up to write about a particular worker sector. The assignment is due Friday February 17, 2017. Normally, students will be required to submit their course essays to Turnitin.com for a review of textual similarity and detection of possible plagiarism. In doing so, students will allow their essays to be included as source documents in the Turnitin.com reference database, where they will be used solely for the purpose of detecting plagiarism. The terms that apply to the University's use of the Turnitin.com service are described on the Turnitin.com web site. This assignment will count for 20 % of your grade in the course.

  • A mid-term examination will be assigned over Reading Week and due Friday February 24, 2017. All readings will be included on the midterm examination. This examination will be worth 30 % of your final mark.

  • Assignment #2 will consist of a structured biosafety risk group assessment of a genus selected from a sign-up sheet. The risk group assessment tool will be provided and should be used to carry out the assignment. We will spend time in class discussing the specifics of this assignment. The assignment is due Friday March 31, 2017. I ask that you submit this assignment to me electronically rather than through turnitin. The assignment will account for 20 % of your final mark.

  • The final examination will take place in the regular class time slot on Monday April 10, 2017 during the normall scheduled class time. This examination will count for 30 % of your final mark. All material from the second module of the course including readings will be tested.