audet lab

Research in the Audet Lab aims at understanding how stem cells proliferate, differentiate and survive and at developing new methods to facilitate their use in regenerative medicine. We are particularly interested in hematopoietic (blood) and neural stem cells. Somatic stem cells are rare and cannot be propagated as immortal cell lines; therefore, studying these cells present significant technical challenges. We have developed novel tools which make it possible to perform quantiative assays at the single-cell level. For instance, we can measure the activity of signaling enzymes in single erythroid (red blood) progenitor cells; we can also track their divisions, up to the 7th generation. The lab has received funding from the National Blood Foundation, the Brain and Behavior Research Foundation, NSERC and CIHR. to know more about our research, you can email the Principal Investigator, Dr. Julie Audet at julie.audet "at" utoronto.ca. More…

somatic stem and progenitor cell engineering

  • julieJulie Audet has obtained her PhD in Chemical and Biological Engineering at the University of British Columbia (2001). She is an Associate Professor of Biomedical Engineering at the University of Toronto. She is also a licensed engineer (P.Eng.). .  . More…
  • ccbrOur laboratory is located in the Donnelly Centre.
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hematopoietic and neural stem cells

  • hematopoiesisHematopoiesis and signaling pathways controling cell fate. More…
  • bloodProduction of red blood cells in vitro using TAT-conjugated transcription factors. More…

analytical and computational tools

  • math modelFlow cytometry, cell division tracking combined with mathematical modeling. More…
  • microscopeSingle-cell capillary electrophoresis and laser lysis. More…