audet lab
Research in the Audet Lab aims at understanding how stem cells proliferate, differentiate and survive and at developing new methods to facilitate their use in regenerative medicine. We are particularly interested in hematopoietic (blood) and neural stem cells. Somatic stem cells are rare and cannot be propagated as immortal cell lines; therefore, studying these cells present significant technical challenges. We have developed novel tools which make it possible to perform quantiative assays at the single-cell level. For instance, we can measure the activity of signaling enzymes in single erythroid (red blood) progenitor cells; we can also track their divisions, up to the 7th generation. The lab has received funding from the National Blood Foundation, the Brain and Behavior Research Foundation, NSERC and CIHR. to know more about our research, you can email the Principal Investigator, Dr. Julie Audet at julie.audet "at" utoronto.ca. More…
somatic stem and progenitor
cell engineering
Julie Audet has obtained her PhD
in Chemical and Biological Engineering at the
University of British Columbia (2001). She is an
Associate Professor of Biomedical Engineering at the
University of Toronto. She is also a licensed
engineer (P.Eng.). . . More…
Our laboratory is located in the
Donnelly Centre.
- . More…
Hematopoiesis
and signaling pathways controling cell fate. 
Production of red
blood cells in vitro using
TAT-conjugated transcription factors. 
Flow cytometry, cell
division tracking combined with
mathematical modeling. 
Single-cell capillary
electrophoresis and laser lysis.