Central Pontine Myelinolysis
Epidemiology:
Common sites:
Gross features:
Histologic features:
- loss of myelin
- relative
preservation of axons and neuronal cell bodies
- symmetric pattern:
- basis pontis
- portions of the pontine tegmentum
- supratentorial compartment
- sparing periventricular and subpial
regions
Immunophenotype:
Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features:
- rapidly evolving
quadriplegia
- occurs in:
- rapid correction
of hyponatremia
- alcoholism
- orthotopic liver transplantation
References: