Germinal matrix intraventricular hemorrhage (IVH)

Epidemiology and Etiology:

· Preterm infants

· Up to 40-50% of infants < 1500g in NICU

· This location is susceptible to damage from hypoxia and changes in perfusion pressure

Common sites:

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Gross features:

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Histologic features:

· Subependymal (germinal matrix) hemorrhage with secondary bleeding into the ventricles

Immunophenotype:

Marker:

Sensitivity:

Specificity:

Molecular features:

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Other features:

· Intraventricular hemorrhages cause sudden increase in intracranial pressure

References:

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