Atypical Lobular Hyperplasia (ALH)

 

Epidemiology:

    •  

 

Common sites:

    •  

 

Gross features:

    •  

 

Histologic features:

    • proliferation of cells identical to those of LCIS except:
      • cells do not fill and distend more than 50% of the acini within a lobule
    • extension into ducts is associated with an increased risk of developing invasive carcinoma

 

Immunophenotype:

Marker:

Sensitivity:

Specificity:

 

 

 

 

Molecular features:

    •  

 

Other features:

    •