Flat Epithelial Atypia (FEA)
Epidemiology:
Common sites:
Gross features:
Histologic features:
- columnar cell
change
- nuclear atypia
- prominent
nucleoli
- rounded nuclei
(rather than oval)
- loss of polarity
- no complex
architecture like rigid bridges or arches or micropapillae
Immunophenotype:
Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features:
- May be a precursor
to ADH
- Associated with
other neoplastic lesions
- Commonly accompanies
tubular carcinoma
References: