Sclerosing Adenosis
Epidemiology:
Common sites:
Gross features:
Histologic features:
- at least twice the
amount of acini per terminal duct compared to
uninvolved lobules
- acini are compressed and distored in the centre, but dilated at the periphery
- prominent myoepithelial cells
- stromal fibrosis
- may completely
compress lumens to create the appearance of solid cords or double
strands
- calcifications
within lumens frequently
- features to
differentiate from invasive carcinoma:
- swirling
arrangement of acini
- well-circumscribed
border
- maintainance of lobular arrangement
Immunophenotype:
Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features: