XYY

Epidemiology and Etiology:

• male

Common sites:

Gross features:

• Increased stature

Histologic features:

Immunophenotype:

Marker:

Sensitivity:

Specificity:

Molecular features:

Other features:

• Psychococial pathology
• High rate of psychiatric referrals
• Low frustration tolerance maybe
• Temper tantrums / aggressive behavior
• Antisocial behavior
• Higher risk with concomitant borderline intelligence or frank metnal deficiency
• Criminal conviction rate increased (mostly minor offenses)
• Motor proficiency impaired maybe
• IQ normal but may be lower than sibs or controls
• Mild learning difficulty (50%)
• Normal sexual activity
• Normal fertility
• No increased risk of aneuploid child

References:

• Gardner & Sutherland (2004)