Indications for Cancer Cytogenetics

· Acute leukemia:

· Diagnostic sample

· After treatment maybe (if abnormality present at diagnosis)

· At relapse maybe

· MDS:

· Diagnostic sample

· After treatment maybe

· Disease progression maybe

· CML:

· Diagnostic sample

· Follow-up for staging maybe

· Monitor effect of treatment maybe

· MPN:

· Diagnostic sample (selected cases)

· Rule out CML

· Assess for possible acute leukemic transformation

· Lymphoma & chronic lymphoproliferative disorders including MM and CLL:

· At diagnosis maybe

· Solid tumours:

· At diagnosis maybe

· Small round cell tumours of childhood

· Selected sarcomas

· Lipomatous tumours

· Others

References:

· CCMG Cytogenetic Practice Guidelines (2003)