Paracentric Inversion X

Epidemiology and Etiology:

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Common sites:

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Gross features:

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Histologic features:

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Immunophenotype:

Marker:

Sensitivity:

Specificity:

Molecular features:

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Other features:

· Child with inv(X)

· Inherited:

· If the inv(X) is associated elsewhere in the family with normality, no defect would be anticipated

· Risk of ovarian failure:

· Breakpoints in critical regions of Xq

References:

· Gardner RJM, Sutherland GR. Chromosome abnormalities and genetic counseling. Oxford University Press; 2004.