DDx - Massive Hepatic Necrosis

• Drugs
• Acetaminophen (40% of all cases)
• Halothane
• Anti-TB drugs (rifampin, isoniazid)
• Monoamine oxidase inhibitors
• Industrial chemicals
• Carbon tetrachloride
• Toxins
• Mushrooms (Amanita phalloides)
• Viral
• Hepatitis B (8%)
• Hepatitis A (4%)