DDx of Steatosis

• EtOH
• Obesity
• Diabetes
• Malnutrition
• TPN
• Wilson
• Hep C virus

• Microvesicular:
• Drugs
• Valproic acid
• Nucleoside analogues
• Acute fatty liver of pregnancy
• Bacterial toxins
• Disorders of ureagenesis

• Fat between cords of liver cells:
• Hypervitaminosis A
• Others

• Zone 3 predominant:
• EtOH
• Obesity
• Diabetes
• Corticosteroids

• Zone 1 predominant:
• Kwashiorkor
• AIDS
• Total parenteral nutrition