Time of Death Determination

 

Overview:

·         Determination of time of death is difficult, imprecise, and often not possible

·          

 

Common sites:

·          

 

Gross features:

·         Livor mortis:

·         Begins at 30 min

·         Note: patients with cardiac failure may develop livor mortis prior to death

·         Fixed livor (very variable)

·         Will not shift if position of body is changed

·         Due to hemolysis and extravasation of blood

·         Rigor mortis:

·         Begins within 2h

·         Jaw -> face -> upper and lower extremities

·         Fully developed 6-12h

·         High temperatures and recent rigorous exercise accelerates the development of rigor

·         Disappearance 36-48 hours (due to decomposition)

·         < 24 h in hot temperatures

·         Several days in cold temperatures

·         Temperature of the body:

·         Not very reliable due to multiple factors

·         Stomach contents:

·         Advanced decomposition:

·         Depends on temperature, humidity

·         24h to 2 weeks in hot to moderate climates

·         Skelatinization:

·         Depends on temperature, scavengers

·         1 week to years

 

Histologic features:

·          

 

Immunophenotype:

Marker:

Sensitivity:

Specificity:

 

 

 

 

Molecular features:

·          

 

Other features:

·         Potassium level of the vitreous:

·         Related to speed of decomposition

·         Not very reliable

·          

 

References:

·         Di Maio VJM, Dana SE. Forensic pathology. Austin, Tex.: Landes Bioscience; 1998.