Pseudomembranous Colitis

 

Epidemiology:

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Common sites:

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Gross features:

    • white plaques which may coalesce to form a sheet
    • background of inflamed mucosa

 

Histologic features:

    • “summit lesion” – first lesion to occur
      • mushroom cloud of pus / fibrin BETWEEN two crypts
    • dilated, necrotic crypts
      • eroded epithelium with classic preservation of basally-located epithelial cells
    • pseudomembranes

 

Immunophenotype:

Marker:

Sensitivity:

Specificity:

 

 

 

 

Molecular features:

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Other features:

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References:

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