Juvenile Myelomonocytic Leukemia (JMML)

 

Epidemiology and Etiology:

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Common sites:

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Gross features:

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Histologic features:

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Immunophenotype:

Marker:

Sensitivity:

Specificity:

 

 

 

 

Molecular features:

·         -7

·         At diagnosis or as a new finding associated with disease acceleration

·         May cooperate with deregulated RAS signaling

 

Other features:

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References:

·         Heim S, Mitelman F. Cancer Cytogenetics. 3rd ed. Wiley-Blackwell; 2009.