-bidi-font-family:"Times New Roman";} @list L9:level2 {mso-bidi-font-family:"Times New Roman";} @list L11:level2 {mso-bidi-font-family:"Times New Roman";} @list L12:level2 {mso-bidi-font-family:"Times New Roman";}

Syphilis (Luetic Lymphadenitis)

(in a lymph node)

Epidemiology and Etiology:

• .

Common sites:

•  .

Gross features:

•  .

Histologic features:

• florid follicular hyperplasia
• interfollicular:
• plasmacytosis
• epithelioid granulomas
• thick, fibrotic capsule
• perivascular plasma cells
• +/- arteritis / phlebitis

Immunophenotype:

Marker:

Sensitivity:

Specificity:

Molecular features:

•  .

Other features:

• serology confirms diagnosis

References:

•  Essentials of Anatomic Pathology, 2^nd Ed (2006)