Neurofibromatosis 2 (NF-2)

Epidemiology and Etiology:

· NF2 defects

· Normal function in cytoskeletal stability

Common sites:

· Brain

· Acoustic nerve (VIII) schwannomas

· meningiomas

Gross features:

·

Histologic features:

·

Immunophenotype:

Marker:

Sensitivity:

Specificity:

Molecular features:

·

Other features:

·

References:

· Kumar V, Fausto N, Abbas A. Robbins & Cotran Pathologic Basis of Disease, Seventh Edition. 7th ed. Saunders; 2004.