Kidney:
Responses to Injury
Epidemiology:
Common sites:
Gross features:
Histologic features:
- Glomerulonephritides:
- Hypercellularity:
- Cellular
proliferation:
- Mesangial
or endothelial cells
- Leukocytic
infiltration:
- Neutrophils, monocytes, lymphocytes
- Crescent
formation:
- proliferating
parietal epithelial cells
- leukocytes
- fibrin
in glomerular tufts and urinary spaces
- basement
membrane thickening:
- thickening
of capillary walls (best seen in PAS stains)
- hyalinization and
sclerosis:
- accumulation
of homogenous eosinophilic material
Immunophenotype:
Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features:
References: