Secondary Biliary Cirrhosis
Epidemiology:
Common sites:
Gross features:
- extraordinary
yellow-green
- hard
- finely granular
Histologic features:
- coarse fibrous septae dividing liver in a jig-saw pattern
- distended small
and large bile ducts in the septa
- inspissated pigmented material in them
- extensive
proliferation of smaller bile ductules
- edema particularly
at the interface between the septa and the parenchyma
- cholestatic features in the parenchyma
- extensive feathery
degeneration
- bile lakes
- neutrophilic infiltration of bile ducts if
ascending bacterial infection
Immunophenotype:
Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features:
References: