Inflammatory (“Allergic”)
Polyp
Epidemiology:
Common sites:
- extending laterally
into the anterior part of the middle meatus
Gross features:
- bilateral
- soft
- grape-like on cut
section
Histologic features:
- loose mucoid stroma
- lymphocytes,
plasma cells, mast cells, neutrophils, eosinophils
- mucous glands
- respiratory
epithelium
- often foci of squamous metaplasia
- prominent
thickening of basal membrane commonly
Immunophenotype:
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Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features:
- local recurrence
often
- choanal
polyp is an
inflammatory polyp arising from one of the sinuses
- may have prominent
vascularity
- associated with mucoviscidosis (cystic fibrosis)
- 6-10% of mucoviscidosis patients have nasal polyps
- may develop as a
complication of mucopolysaccharoidosis (Hurler-Scheie syndrome)