Odontoma

 

Epidemiology:

    • Most common type of odontogenic tumour
    • Children
    • Teenagers

 

Common sites:

    •  

 

Gross features:

    • miniature teeth may be present (compound odontoma)

 

Histologic features:

    • mixture of soft and hard material
    • extensive depositions of enamel and dentin
      • dentin looks like bone, but has many parallel tubules running through it, quite close together.
      • Enamel matrix looks fishscales
    • remnants of cells that make the above
      • pulp is loose connective tissue with a peripheral layer which makes the dentin next to it
        • lined by odontoblasts – columnar cells
      • reduced enamel epithelium
        • 2 layers of columnar cells

 

Immunophenotype:

Marker:

Sensitivity:

Specificity:

 

 

 

 

Molecular features:

    •  

 

Other features:

    • hamartomas probably
    • usually presents as non-erupting tooth à radiograph
      • usually gets in the way of an erupting tooth
    • cured by local excision

 

References:

    • Robbins 2005
    • Mod Surg Path 2003