Small Cell Carcinoma of the Prostate

 

Epidemiology:

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Common sites:

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Gross features:

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Histologic features:

    • similar cytological appearance to that in the lung
    • 50% are mixed with adenocarcinoma (no difference in behaviour)

 

Immunophenotype:

Marker:

Sensitivity:

Specificity:

 PSA (neg)

 

 

PSAP (neg)

 

 

 

Molecular features:

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Other features:

    • very poor survival (avg < 1y)
    • ACTH or antidiuretic hormone may be clinically evident(uncommon)

 

References:

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