Monomorphic adenoma
Epidemiology:
Common sites:
- canalicular most common in upper lip
Gross features:
Histologic features:
- epithelial tumour lacking the mesenchymal
component associated with pleomorphic adenoma
- trabecular, tubular, canalicular
- trabecular:
- cords of solid
cells 3-4 layers thick
- well-demarcated
by basal membrane
- tubular:
- appearance of
salivary ducts, with distinct lumens
- lumen contains PAS-positive secretions
- basal membrane delimiting
individual ductal
structures
- canalicular:
- tubules or
ducts lined by cuboidal cells
- usually devoid
of myoepithelial cells
Immunophenotype:
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Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features: