Pigmented
Purpuric Dermatitis
Epidemiology and Etiology:
Common sites:
Gross features:
- orange/brown
pigmentation
- interspersed
pinpoint (cayenne pepper-like) purpura
- multiple clinicopathologic
patterns
- telangiectasia may
be prominent
Histologic features:
- superficial dermal
perivascular lymphocytic infiltrate
- vascular damage
(limited)
- endothelial cell
swelling
- focal
karyorrhectic debris
- extravasation of
RBCs
- hemosiderin
- may see:
- spongiosis
- basal layer
vacuolopathy
Immunophenotype:
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Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features:
References: