Erythema Induratum

Epidemiology:

• Adolescents and menopausal women

Common sites:

• Lower legs

Gross features:

• Erythematous nodule
• Usually progresses to ulceration

Histologic features:

• Early lesion:
• Necrotizing vasculitis of small to medium-sized arteries and veins in the deep dermis and subcutis
• Granulomatous inflammation of the fat lobule
• Zones of caseous necrosis

Immunophenotype:

Marker:

Sensitivity:

Specificity:

Molecular features:

Other features:

References:

• Robbins 2005