Halo Nevus

Epidemiology:

• adolescence

Common sites:

Gross features:

• pre-existing nevus develops a surrounding rim of hypopigmentation
• gradual disappearance of nevus over several months
• repigmentation of halo usually follows

Histologic features:

• nevus of any type with dense lymphocytic infiltrate
• lymphocytes densely arranged, obscuring underlying melanocytic lesion
• focal atypical nevus cells

Immunophenotype:

Marker:

Sensitivity:

Specificity:

Molecular features:

Other features:

• may occur in patients with concurrent melanoma
• may occur in setting of vitiligo

References:

• Essentials of AP 2006
• Skin Disease: Diagnosis and Treatment – Habif (2001)