Papillary Eccrine Adenoma

Tubulopapillary Hidradenoma

Epidemiology and Etiology:

· African females

Common sites:

· Lower extremities

Gross features:

·

Histologic features:

· Poorly circumscribed

· Duct-like structures of variable size

· Distinctive luminal micropapillary fronds

· Cuboidal epithelium 2 or more cells thick

· Configuration similar to florid ‘simple’ intraductal hyperplasia in the breast

· Focal luminal “pseudonecrotic” secretion

· Lack of macrocysts as seen in digital papillary adenocarcinoma

· May have apocrine differentiation

· Squamous or clear cell metaplasia maybe

Immunophenotype:

Marker:

Sensitivity:

Specificity:

Molecular features:

·

Other features:

·

References:

· Silverberg SG, DeLellis RA, Frable WJ, LiVolsi VA, Wick MR. Silverberg's Principles and Practice of Surgical Pathology and Cytopathology: 2-Volume Set. 4th ed. Churchill Livingstone; 2005.