Bacillary Angiomatosis
Epidemiology:
Common sites:
- Skin
- Bone
- Brain
- Other organs
- Bacillary peliosis in liver and spleen
Gross features:
- One or numerous red
subcutaneous papules and nodules
- Rounded subcutaneous
masses
Histologic features:
- Tumour-like proliferation of capillaries
- Protruberant epithelioid
endothelial cells
- Numerous stromal neutrophils
- Nuclear dust
- Purplish granular
material (causative bacteria)
Immunophenotype:
Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features:
- opportunistic
infection of immunocompromised persons
- Bartonella
henselae – gram negative bacilli (cat scratch)
- Bartonella
quintana – (trench fever)
- Difficult to
culture
- PCR can detect them
- Domestic cat is
reservoir
- Cat flea is vector
References: