Gangliocytic Paraganglioma
Epidemiology:
Common sites:
Gross features:
- soft yellowish cut
section
- infiltrative
border
- GI tract:
- Submucosal lesion with minor extensions into
mucosa
Histologic features:
- 3 cell types in
variable proportions:
- spindle cells with
appearance of nerve sheath cells
- ganglion-like
cells
- epithelioid cells:
- “endocrine”-like
nests, trabeculae, papillary structures
- GI tract:
- Submucosal lesion
- Minor extensions
into mucosa
Immunophenotype:
Marker:
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Sensitivity:
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Specificity:
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Molecular features:
Other features:
References:
- Gastrointestinal
and Liver Pathology 2005