Myxofibrosarcoma
Epidemiology:
Common sites:
Gross features:
Histologic features:
- at
least 10% myxoid areas
- pleomorphism is present
- fibroblastic
appearance of cells
- thick-walled
vessels often curved with a wide arc
- associated
with an eosinophilic substance
- adherent
tumour cells
- non-myxoid MFH-like areas often
Immunophenotype:
Marker:
|
Sensitivity:
|
Specificity:
|
S-100 (neg)
|
|
|
Molecular features:
Other features:
- gradually
coming to be used to encompass all cases of myxoid
MFH
- local
recurrence may occur
- unlikely
to metastasize
References: