Radiation Effects

 

Epidemiology:

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Common sites:

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Gross features:

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Histologic features:

    • sarcomas:
      • impossible to assess tumour type (differentiation may change)
      • skeletal muscle in field may look mildly atypical
        • multiple nuclei in collapsed fibre
      • thickening of blood vessel walls

 

Immunophenotype:

Marker:

Sensitivity:

Specificity:

 

 

 

 

Molecular features:

    •  

 

Other features:

    • Induction of cancer:
      • Osteogenic sarcomas

 

References:

    • Robbins 2005