Had at least one vaso-occlusive episode in the previous year
Yes No

Sickle genotype
HbSS or S/B0 HbSC or S/B+

History of multiple transfusions before pregnancy
Yes No

History of cardiac complications
Yes No

hemoglobin (g/L) in the first trimester

Prediction Rules for Identification of Women with Sickle Cell Disease at Risk of Adverse Pregnancy Outcomes.
Ann Kinga Malinowski^1,2,7 MD, MSc; Kevin H. M. Kuo^3,7 MD, MSc; George A. Tomlinson^4,5 PhD; Richard Ward^3,7 MRCP, FRCPath, MSc; Nadine Shehata^3,5-7 MD, MSc.
¹ Mount Sinai Hospital, Department of Obstetrics and Gynaecology, Division of Maternal-Fetal Medicine, Toronto, Canada
² Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada
³ University Health Network, Department of Medicine, Division of Medical Oncology and Haematology, Toronto, Canada
⁴ University Health Network, Department of Medicine, Toronto, Canada
⁵ Institute of Health Policy, Management and Evaluation, University of Toronto, Canada
⁶ Mount Sinai Hospital, Department of Medicine, Division of Haematology, Toronto, Canada
⁷ University of Toronto, Department of Medicine, Toronto, Canada

The authors acknowledge Shekeb Khan, PhD, for building the online calculator