Moffat Lab Homepage

Our lab uses lentiviral RNAi and imaging technologies to understand how different growth signaling pathways contribute to cancer metabolism.

Introduction

The era of systematic genetic analyses of mammalian cultured cells has now arrived with the discovery of RNA interference. We are making use of lentiviral-mediated RNAi technology and high-content screening to systematically uncover genes that function in growth signaling pathways to influence cancer metabolism.

Our laboratory is located in the newly constructed Donnelly Centre for Cellular and Biomolecular Research (CCBR), located within the main University of Toronto campus and Toronto discovery district.

News

Link to the Portal, OICR's quarterly newsletter, and read the story about the Moffat Lab by Steve Durant (Fall 2007).

Combining viruses and image-analysis techniques to discover genes in mitosis as described in Paradigm Magazine (Fall 2006).