Selected Lab Publications
The DIAPH3 linker specifies a b-actin netwrok that maintains RhoA and Myosin-II at the cytokinetic furrow Shah, R., Panagiotou, T.C., Cole, G.B., Moraes, T.F., Lavoie, B.L., McCulloch, C.A., and Wilde, A. Nature Communications. 2024 15, 5250
Mechanics and regulation of mitotic exit and cytokinesis D'Avino, P.P., Vagnarelli, P. and Wilde, A. Front. Cell Dev. Biol. 2023 11
An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis. Panagiotou, T.C., Chen, A. and Wilde, A. Cell Reports 2022 40:111274
A lipid primes the final cut in dividing cells. Brill, J. A. and Wilde, A. Science. 2021 374:1318-1319
Inhibition of polar actin assembly by astral microtubules is required for cytokinesis. Chen, A., Ulloa Severino, L., Panagiotou, T.C., Moraes, T.F., Yuen, D.A., Lavoie, B.D. and Wilde, A. Nature Communications 2021 12:2409
Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodelling. Arora, P.D., Nakajima, A., Nanda, A., , J.W., Plaha, A., Wilde, A., Sacks, D.B. and McCulloch, C.A., L Mol. Biol. Cell 2020 31:1595-1610
The scaffold-protein IQGAP1 enhances and spatially restricts the actin nucleating activity of Diaphanous-related formin 1 (DIAPH1). Chen A., Arora, P.D., Lai, C.C., Copeland, J.W., Moraes, T.F., McCulloch, C.A., Lavoie, B.D. and Wilde, A. J. Biol. Chem. 2020 295: 3134-3147
CDK11p58-CyclinL1b regulates abscission site assmebly. Renshaw, M.J., Panagiotou, T.C., Lavoie, B.D. and Wilde, A. J. Biol. Chem. 2019 294: 18639-18649
Cytokinesis requires localized b-actin filament production by an actin isoform specific nucleator. Chen A., Arora, P.D., McCulloch, C.A. and Wilde, A. Nature Communications 2017 8:1530
Importin b2 mediates the spatio-temporal regulation of anillin through a nancanonical nuclear localization signal. Chen A., Akhshi TK., Lavoie BD., Wilde, A. J. Biol. Chem. 2015 290:13500-13509
Anillin-dependent organization of septin filaments promotes intercellular bridge elongation and Chmp4B targeting to the abscission site. Renshaw, M.J., Liu, J., Lavoie, B.D and Wilde, A. Open Biol.. 2014 4:130190
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