|Cell division is the process where 1 cell divides to become 2 cells. It is the most visually exciting function the cell carries out. During cell division it is crucial that the genome in the original, mother cell is divided equally between the 2 new daughter cells. Any failure in this process can result in genome instability and aneuploidy, hallmarks of tumor cells.
Our goal is to understand the molecular details of cell division in normal cells and tumor cells in order to understand how cancers form.
We take a multi-faceted approach to understand cell division. By exploiting the specialized biology of frog oocytes, fruit fly embryos and mammlian tisue culture cells we can examine different aspects of cell division in much greater detail than focusing on one system.