|
Publications
|
|||||
|
Mechanics and regulation of mitotic exit and cytokinesis An anillin-CIN85-SEPT9 complex promotes intercellular bridge maturation required for successful cytokinesis A lipid primes the final cut in dividing cells Inhibition of polar actin assembly by astral microtubules is required for cytokinesis Flightless anchors IQGAP1 and R-ras to mediate cell extension formation and matrix remodelling The scaffold-protein IQGAP1 enhances and spatially restricts the actin nucleating activity of Diaphanous-related formin 1 (DIAPH1) CDK11p58-CyclinL1b regulates abscission site assmebly Cytokinesis requires localized b-actin filament production by an actin isoform specific nucleator Importin b2 mediates the spatio-temporal regulation of anillin through a nancanonical nuclear localization signal Anillin-dependent organization of septin filaments promotes intercellular bridge elongation and Chmp4B targeting to the abscission site Glycolytic metabolites are critical modulators of oocyte maturation and viability The BAR domain of Amphiphysin is required for pseudocleavage furrow tip (PFT)-tubule A bacterial acetyltransferase destroys plant microtubule networks and blocks secretion Cleavage furrow organization requires PIP2-mediated recruitment of anillin Phosphoinositide function in cytokinesis Chlamydia trachomatis Inclusions Induce Asymmetric Cleavage Furrow Formation and Ingression Failure in Host Cells The site of RanGTP generation can act as an organizational cue for mitotic microtubules. The role of the Ran GTPase in mitotic spindle assembly The Fowler syndrome-associated protein FLVCR2 is an importer of heme. Poleward transport of TPX2 in the mammalian mitotic spindle requires dynein, Eg5, and microtubule flux. Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase. Conservation of core gene expression in vertebrate tissues. Ran out of the nucleus for apoptosis. Anillin-mediated targeting of peanut to pseudocleavage furrows is regulated by the GTPase Ran. "HURP on" we're off to the kinetochore! Ran is required before metaphase for spindle assembly and chromosome alignment and after metaphase for chromosome segregation and spindle midbody organization. Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. Structural basis for the activation of microtubule assembly by the EB1 and p150Glued complex. The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis. Ran modulates spindle assembly by regulating a subset of TPX2 and Kid activities including Aurora A activation. Bst-2/HM1.24 is a raft-associated apical membrane protein with an unusual topology. Ran localizes around the microtubule spindle in vivo during mitosis in Drosophila embryos. Characterization of the effects of RanGTP on the microtubule cytoskeleton. Ran stimulates spindle assembly by changing microtubule dynamics and the balance of motor activities. Role of Importin-b in coupling Ran to downstream targets in microtubule assembly. The role of Xgrip210 in g-tubulin ting complex assembly and centrosome recruitment. Complete reconstitution of clathrin basket formation with recombinant protein fragments: adaptor control of clathrin self-assembly. NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. Stimulation of microtubule aster formation and spindle assembly by the small GTPase Ran. EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. In vivo phosphorylation of adaptors regulates their interaction with clathrin. The tyrosine-containing internalization motif in the cytoplasmic domain of TGN38/41 lies within a nascent helix. Epitope mapping of two isoforms of a trans Golgi network specific integral membrane protein TGN38/41. Identification, molecular characterization and immunolocalization of an isoform of the trans-Golgi-network (TGN)-specific integral membrane protein TGN38. A simple single-step procedure for small-scale preparation of Escherichia coli plasmids. |
|||||