Lymphoma
Pathophysiology: Hodgkin's and non-Hodgkin's lymphoma typically involve the thorax. Rarely, other “lymphoreticular” neoplasms may occur.
CXR/CT findings:
- mediastinal and/or hilar adenopathy
- solitary or multiple generally bulky lung masses
- pleural effusions
- pericardial effusion
- rarely in untreated disease, associated atelectasis
- rarely, bone thoracic cage involvement.
Clues to Distinguishing Hodgkin's from Non-Hodgkin's Lymphoma:
Hodgkin's: generally symmetric hilar and mediastinal adenopathy
Non Hodgkin's: asymmetric, bulky mediastinal or hilar adenopathy often with effusions and lung involvement
Bottom Line: needs tissue diagnosis
Staging Imaging:
- CXR
- CT thorax/abdomen
- Abdominal/pelvic US
- Rarely others: GI studies, MRI, bone scanning
"Aunt Sophies":
Metastatic adenopathy
Lung cancer and adenopathy
Infections (eg. tuberculosis and fungal)
Castleman's disease
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