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Pleural Effusion

Pathophysiology:  

 

Transudative: Essential consists of water and electrolytes, seen in CHF, renal failure, hypoproteinemic states and fluid overload states.

 

Exudative: Multiple causes: infections (para-pneumonic effusions with community acquired pneumonia CAP), tuberculous effusions, hemothorax (bleeding of any cause), malignant effusions (eg. metastases, lymphoma), pulmonary embolism, collagen vascular diseases (SLE, rheumatoid lung disease, scleroderma, mixed CTD).

 

Chylothorax: Lymph in the pleural space.  Rarely seen.  Injury or disruption of the thoracic duct as seen in lymphangioleiomyomatosis (LAM).

 

CXR Findings:

 

  1. Classic “meniscus sign” with pleural effusion curving to chest wall, seen on PA and lateral films

  2. Blunting of the costo-phrenic sulcus

  3. Hemithorax “white-out”

  4. Associated passive or relaxation atelectasis in lung bases

  5. May see mediastinal shift in large effusions

 

Imaging Clues:

 

  1. Need about 150 cc of fluid in the pleural space to see on routine PA and lateral films

  2. Decubitus views may show as little as 15 cc of fluid (rarely done as not suspected on routine CXR)

  3. Uncomplicated effusions always associated with relaxation atelectasis.  The volume loss is more or less the same as the pleural effusion in small to moderate effusions so overall no volume change in hemithorax.  In large effusions, the fluid volume is larger than the atelectatic volume loss and mediastinum may shift to contralateral side.

  4. Big Clue: if the pleura is encased, fibrotic or thickened, or if the mediastinum is involved with pathology. There will be variations and exceptions to these principles.

  5. Pseudo-tumor: the effusion may encyst or loculate, simulating a lung mass or tumor

 

“Aunt Sophies”:

 

  1. Atelectasis

  2. Pleural fibrosis

  3. Pleural tumor (eg. mesothelioma, metastastic disease)

  4. Extrapleural fat

 


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