Curriculum Vitae [pdf]

Curriculum Vitae

Hatef Mehrabian, PhD

Curriculum vitae 

Address:

Dept. of Medical Biophysics

University of Toronto
Sunnybrook Research Institute
2075 Bayview Avenue, Room S6-05
Toronto, ON  M4N 3M5 CANADA

Tel:

+1-416-480-6100 x.2455

April 2016

 

Email:

hatef.mehrabian@sri.utoronto.ca

Website:

http://individual.utoronto.ca/hatefmehrabian


EDUCATION and QUALIFICATIONS

Jan 2015 - Present

Postdoctoral Research Fellow

Dept. of Physical Sciences, Sunnybrook Research Institute

Dept. of Medical Biophysics, University of Toronto

Toronto, ON, Canada

Advisor: Greg J. Stanisz

Mar 2014 - Dec 2014

Postdoctoral Research Fellow

Dept. of Physical Sciences, Sunnybrook Research Institute

Dept. of Medical Biophysics, University of Toronto

Toronto, ON, Canada

Advisor: Anne L. Martel

Jan 2009 - Feb 2014

Ph.D. in Medical Biophysics

Dept. of Medical Biophysics, University of Toronto

Toronto, ON, Canada

Supervisor: Anne L. Martel

Thesis: Application of Independent Component Analysis (ICA) in Pharmacokinetic Modeling of Tumors Using Dynamic Contrast Enhanced (DCE)-MRI

Jan 2007-Dec 2008

M.E.Sc in Electrical Engineering, Biomedical

Dept. of Electrical and Computer Eng., University of Western Ontario

London, ON, Canada

Supervisor: Abbas Samani 

Thesis: Soft tissue hyperelastic parameter reconstruction for breast cancer assessment

Sept 2002-Aug 2006

B.Sc. in Electrical Engineering, Control

School of Electrical and Computer Eng., University of Tehran

Tehran, Iran   

Supervisor: Babak N. Araabi

Thesis: Design and Implementation of an Iris Recognition algorithm based on Iris Image Analysis

 

CERTIFICATES

October 2015

SIEMENS MRI Pulse Sequence Programming

IDEA Sequence Development Environment programming (SDE)

University of Western Ontario, London, ON, Canada

 

October 2015

SIEMENS MRI Pulse Sequence Programming

IDEA Imaging Calculation Environment programming (ICE)

University of Western Ontario, London, ON, Canada

 

February 2015

Comparative Research Animal Care, Sunnybrook Research Institute

Toronto, Ontario, Canada

 

November 15, 2013

CIHR Tram Grant & OICR Smarter Imaging Program (SIP) – Prostate Workshop “Imaging Applications in Prostate Cancer”

London, Ontario, Canada

 

November 16, 2012

CIHR Tram Grant & OICR Smarter Imaging Program (SIP) – Prostate Workshop “Imaging Applications in Prostate Cancer”

London, Ontario, Canada

 

May 2007

Teaching Assistant Training Program (TATP)

University of Western Ontario, London, ON, Canada

 

PUBLICATIONS

Book Chapters

September, 2014

Blind Source Separation in Assessing Tumor Pharmacokinetics (Chapter 13)

Author: Hatef Mehrabian (sole Author)

Book Title: Frontiers of Medical Imaging (Part II)

Editor: Chi Hau Chen (University of Massachusetts Dartmouth)

Publisher: World Scientific Publishing (WSPC), Imperial College Press

 

Journal Articles

[1] Mehrabian, H., Da Rosa M., Haider, M. A., and Martel, A. L., “Pharmacokinetic Analysis of Prostate Cancer Using Independent Component Analysis”, Magnetic Resonance Imaging (MRI)33 (10), pp. 1236-1245, (2015). [PDF] [HTML]

[2] Mehrabian, H., Chopra, R., and Martel, A. L., “Calculation of intravascular signal in dynamic contrast enhanced MRI using adaptive complex independent component analysis”, IEEE Transactions on Medical Imaging32 (4), pp. 699-710, (2013). [PDF] [HTML]

[3]  Mehrabian, H., Chandrana, C., Pang, I., Chopra, R., and Martel, A. L., “Arterial input function calculation in dynamic contrast-enhanced MRI: an in vivo validation study using co-registered contrast-enhanced ultrasound imaging”, European Radiology 22 (8), pp. 1735-1747, (2012). [PDF] [HTML]

[4] Mehrabian, H.Lindvere, L., Stefanovic, B., and Martel, A. L., “A constrained independent component analysis technique for artery-vein separation of two-photon laser scanning microscopy images of the cerebral microvasculature”, Medical Image Analysis, 16 (1), pp. 239-251, (2012).[PDF][HTML]

[5]  Mehrabian, H., Campbell, G.  and Samani, A., “A constrained reconstruction technique of hyperelasticity parameters for breast cancer assessment ”, Physics in Medicine and Biology 54 (24), pp. 7489-7508, (2010). [PDF][HTML]

 

Conference Papers

[1]   Mehrabian, H.,  Desmond K. L., Sahgal A., Soliman H., Martel A. L., and Stanisz, G. J., “Intracellular-extracellular water exchange as a biomarker of tumor response to stereotactic radiosurgery”, 24th Annual Meeting of International Society of Magnetic Resonance in Medicine, Singapore, Singapore, May 07-13, 2016. (Summa Cum Laude Award) [HTML]

[2]   Mehrabian, H.,  Desmond K. L., Martel A. L., Sahgal A., Soliman H., and Stanisz, G. J., “Chemical exchange saturation transfer (CEST) and relaxometry as biomarkers for assessing response of brain metastases to stereotactic radiosurgery”, 24th Annual Meeting of International Society of Magnetic Resonance in Medicine, Singapore, Singapore, May 07-13, 2016.[HTML]

[3]   Desmond, K. L., Mehrabian, H.,  Sahgal A., Soliman H., and Stanisz, G. J., “CEST Metrics for Assessing Early Response to Stereotactic Radiosurgery in Human Brain Metastases”, 24th Annual Meeting of International Society of Magnetic Resonance in Medicine, Singapore, Singapore, May 07-13, 2016.[HTML]

[4]   Desmond, K. L., Mehrabian, H.,  Chavez, S., Sahgal A., Soliman H., and Stanisz, G. J., “Chemical Exchange Saturation Transfer (CEST) Metrics for Assessment of Early Response to Stereotactic Radiosurgery in Human Brain Metastases”, 14th Annual Imaging Network of Ontario Symposium (ImNO), Toronto, ON, Canada, March 30-31, 2016. (Magna Cum Laude Award) [HTML]

[5]   Desmond, K. L., Mehrabian, H.,  Chavez, S., Sahgal A., Soliman H., and Stanisz, G. J., “Chemical Exchange Saturation Transfer (CEST) Metrics for Assessing Early Response to Stereotactic Radiosurgery in Human Brain Metastases”, Chemical Exchange Saturation Transfer Symposium (PENN-CEST 2015), Philadelphia, PA, USA, October 25-28, 2015.[PDF]

[6]   Mehrabian, H.,  Martel, A. L., Le Floc’h J., Soliman H.,, Sahgal, A., and Stanisz, G. J., “Quantification of Water Exchange Between Intravascular and Extravascular Components Using Independent Component Analysis”, 23rd Annual Meeting of International Society of Magnetic Resonance in Medicine, Toronto, ON, Canada, May 30- June 05, 2015.[PDF][HTML]

[7]   Mehrabian, H., Haider, M. A., and Martel, A. L., “Local Vascular Input Function for Pharmacokinetic Modeling of Prostate Cancer”, Joint Annual Meeting of ISMRM-ESMRMB, Milan, Italy, May 10-16, 2014.[PDF][HTML]

[8]   Mehrabian, H., Haider, M. A., and Martel, A. L., “Assessing the Effects of Decreasing Temporal Resolution on Pharmacokinetic Analysis Using a Local Vascular Input Function”, Joint Annual Meeting of ISMRM-ESMRMB, Milan, Italy, May 10-16, 2014.[PDF][HTML]

[9]   Mehrabian, H., Haider, M. A., and Martel, A. L., “Using Independent components analysis to calculate intravascular contrast agent concentration in prostate cancer”, Biomedical Imaging: From Nano to Macro, IEEE International Symposium on, San Francisco, CA, USA, April 7-11, (2013).[PDF]

[10]   Mehrabian, H., Pang, I., Chopra, R., and Martel, A. L., “An adaptive complex independent component analysis to analyze dynamic contrast enhanced-MRI”, Biomedical Imaging: From Nano to Macro, IEEE International Symposium on, Barcelona, Spain, May 2-5, (2012).[PDF]

[11]   Mehrabian, H., Pang, I., Chandrana, C., Chopra, R., Martel, A.L., "Automatic mask generation using independent component analysis in dynamic contrast enhanced-MRI," Biomedical Imaging: From Nano to Macro, IEEE International Symposium on , Chicago, IL, USA, March 30 - April 2, (2011).[PDF]

[12]   Mehrabian, H.Lindvere, L., Stefanovic, B., and Martel, A. L., “Deconvolution of dynamic dual photon microscopy images of cerebral microvasculature to assess the hemodynamic status of the brain”, in Medical Imaging 2011: Biomedical Applications in Molecular, Structural, and Functional Imaging, Proceedings of SPIE Vol. 7965 (2011) 79650A-1.[PDF]

[13]   Mehrabian, H.Lindvere, L., Stefanovic, B., and Martel, A. L., “A temporally constrained ICA (TCICA) technique for artery-vein separation of cerebral microvasculature”, in Medical Imaging 2010: Biomedical Applications in Molecular, Structural, and Functional Imaging, Proceedings of SPIE Vol. 7626 (2010) 762622.[PDF]

[14]   Mehrabian, H., Samani, A., "Constrained hyperelastic parameters reconstruction of PVA (Polyvinyl Alcohol) phantom undergoing large deformation" in Medical Imaging 2009: Visualization, Image-Guided Procedures, and Modeling, Proceedings of SPIE Vol. 7261 (2009) 72612G.[PDF]

[15]   Mehrabian, H., Karimi, H., Samani, A., "Accurate optical flow field estimation using mechanical properties of soft tissues" in Medical Imaging 2009: Biomedical Applications in Molecular, Structural, and Functional Imaging, Proceedings of SPIE Vol. 7262 (2009) 72621B.[PDF]

[16]   Mehrabian,  H., Samani, A., "An iterative hyperelastic parameters reconstruction for breast cancer assessment" in Medical Imaging 2008: Physiology, Function, and Structure from Medical Images, Proceedings of SPIE Vol. 6916 (2008) 69161C.[PDF]

[17]   Mehrabian, H., Hashemi-Tari, P., “Pupil Boundary Detection for Iris Recognition Using Graph Cuts”, Proceedings of Image and Vision Computing New Zealand 2007, pp. 77–82, Hamilton, New Zealand, December 2007.[PDF]

[18]   Mehrabian,  H.Poursaberi, A., Araabi, B. N., “Feature Extraction for Iris Recognition Using Gabor Filters and Daubechies2 Wavelet Transform and Sensitivity Analysis”, 4th Iranian Conference on Machine Vision and Image Processing (MVIP), February 2007, Mashhad, Iran.[PDF]

[19]   Mehrabian, H.Poursaberi, A., Araabi, B. N., “Iris Boundary Detection for Iris Recognition Using Laplacian Mask and Hough Transform”, 4thIranian Conference on Machine Vision and Image Processing (MVIP), February 2007, Mashhad, Iran.[PDF]

[20]    Ashouri, A., Mehrabian, H., "Optimizing Fuzzy Controller for Reverse Pendulum System Using Genetic Algorithm". 2nd ECESYMP paper contest, Tehran, Iran, February 2006.[PDF]

 

Abstracts

[21]   Mehrabian, H., Haider, M. A., and Martel, A. L., “Pharmacokinetic Modeling of Prostate Tumor Using Independent Component Analysis”, 12th Imaging Network of Ontario Symposium, Toronto, Ontario, Canada, March 24-25, 2014.

[22]   Mehrabian, H., Haider, M. A., and Martel, A. L., “Local vascular input function (VIF) calculation for prostate cancer assessment”, Imaging Applications in Prostate Cancer Workshop, London, ON, Canada, November 15, 2013.

[23]   Mehrabian, H., Haider, M. A., and Martel, A. L., “Pharmacokinetic analysis of prostate cancer using independent components analysis”, Imaging Applications in Prostate Cancer Workshop , London, ON, Canada, November 16, 2012.

[24]   Mehrabian, H., Chandrana, C., Pang, I., Chopra, R., and Martel, A. L., “Calculating arterial input function in dynamic contrast enhanced-MRI of tumors: A validation study”, Invited to the Canadian Student Health Research Forum (CSHRF). Winnipeg, MB, Canada, June 12-14, 2012.

 

AWARDS and HONORS

2016-2018

NSERC-PDF (Natural Sciences and Engineering Research Council of Canada Postdoctoral Fellowship)

 

May 2016

Summa Cum Laude Award, ISMRM (2016)

International Society for Magnetic Resonance in Medicine (ISMRM), Singapore, Singapore

 

March 2016

JMRI Certificate of Appreciation

Journal of Magnetic Resonance Imaging (JMRI)

 

March 2016

Magna Cum Laude Award, ImNO (2016)

14th Annual Imaging Network of Ontario Symposium (ImNO), Toronto, ON, Canada

 

Sept 2013-Sept 2014

Ontario Graduate Scholarship (OGS)

 

Sept 2012-Sept 2013

Queen Elizabeth II Graduate Scholarship in Science & Technology (QEII-GSST)

 

Sept 2011-Sept 2012

Ontario Graduate Scholarship (OGS)

 

Sept 2013-Sept 2014

MBP (Medical Biophysics) Excellence UTF (University of Toronto Fellowship) Scholarship

University of Toronto, Toronto, ON, Canada

 

Sept 2012-Sept 2013

MBP (Medical Biophysics) Excellence UTF (University of Toronto Fellowship) Scholarship

University of Toronto, Toronto, ON, Canada

 

Sept 2011-Sept 2012

MBP (Medical Biophysics) Excellence UTF (University of Toronto Fellowship) Scholarship

University of Toronto, Toronto, ON, Canada

 

Sept 2010-Sept 2011

MBP (Medical Biophysics) Excellence UTF (University of Toronto Fellowship) Scholarship

University of Toronto, Toronto, ON, Canada

 

Jan 2009-Sept 2010

University of Toronto Fellowship

University of Toronto, Toronto, ON, Canada

 

Jan 2007-Dec 2008 

Western Graduate Research Scholarship (WGRS)

University of Western Ontario, London, ON, Canada

 

May 2016 

ISMRM Trainee (Educational) Stipend

24th Annual meeting of ISMRM, May 7-13, Singapore, Singapore  

 

May 2015 

ISMRM Trainee (Educational) Stipend

23rd Annual meeting of ISMRM, May 30 - June 05, Toronto, ON, Canada  

 

February 2015 

ISMRM Workshop Trainee (Educational) Stipend

ISMRM Workshop on MRI in the Management of Breast Disease, Feb 12-15, San Francisco, CA, USA  

 

May 2014 

ISMRM Trainee (Educational) Stipend

to attend Joint Annual meeting ISMRM-ESMRMB, May 10-16, Milan, Italy  

 

June 2014

Sunnybrook Trainee Travel Award

Sunnybrook Research Institute, Toronto, ON, Canada

 

May 2013

MBP (Medical Biophysics) 50th Anniversary Student Travel Award

University of Toronto, Toronto, ON, Canada

 

June 2013

Sunnybrook Trainee Travel Award

Sunnybrook Research Institute, Toronto, ON, Canada

 

June 2012

MBP (Medical Biophysics) 50th Anniversary Student Travel Award

University of Toronto, Toronto, ON, Canada

 

May 2012

Sunnybrook Trainee Travel Award

Sunnybrook Research Institute, Toronto, ON, Canada

 

May 2012

School of Graduate Studies Conference Grant

University of Toronto, Toronto, ON, Canada

 

Sept 2011-Sept2012

MBP (Medical Biophysics) Visa Scholarship

University of Toronto, Toronto, ON, Canada

 

December 2008

Graduate Thesis Research Award (GTRA)

University of Western Ontario, London, ON Canada

 

INVITED TALKS

Oral Presentations 

June 20, 2011

Fields-MITACS: Conference on Mathematics of Medical

June 20-24, 2011, Toronto, ON, Canada

Talk Title: Application of Independent Component Analysis (ICA) to Identify and Separate Tumor Arterial Input Function (AIF) in Dynamic Contrast Enhanced MRI

Feb 03, 2011

Sunnybrook Medical Image Analysis Laboratories (SMIAL) Seminar

Sunnybrook Research Institute, Toronto, ON, Canada

Talk Title: Deconvolution of dynamic dual photon microscopy images of cerebral microvasculature to assess the hemodynamic status of the brain

 

Poster Presentations  

June 13, 2012

Canadian Student Health Research Forum (CSHRF)

June 12-14, 2012, Winnipeg, MB, Canada

Poster Title: Calculating Arterial Input Function in Dynamic Contrast Enhanced MRI of Tumors: A Validation Study

 

TEACHING EXPERIENCE

Sep 2008-Dec 2008

Teaching Assistant for the course ECE 2240A: Electrical Laboratory

Instructor: L. Marinov

University of Western Ontario, London, ON, Canada

Jan 2008-April 2008

Teaching Assistant for the course BME 502B: Engineering Analysis of Physiological Systems

Instructor: J. C. Lacefield

University of Western Ontario, London, ON, Canada

Sept 2007-Dec 2007

Teaching Assistant for the course ECE 311A: Signals, Systems & Software Processes

Instructor:  J. C. Lacefield

University of Western Ontario, London, ON, Canada

Jan 2007-April 2007

Teaching Assistant for the course ECE 239B: Electrical & Electronic Circuits

Instructor: A. R. Masoleh

University of Western Ontario, London, ON, Canada

           

COMPUTER KNOWLEDGE

Programming Languages

C, C++ , Verilog, Assembly, MATLAB, IDL, R

Engineering Software

IDL, ABAQUS (FE Solver), PSpice, HSpice, ModelSim, Quartus, MATLAB, SIMATIC MANAGER

 

GRADUATE COURSES

Spring 2011

Clinical Imaging for Physical Scientists

Instructor: Peter Burns

University of Toronto, Toronto, ON, Canada

Fall 2009

Advanced Medical Imaging

 Instructor: Simon Graham

University of Toronto, Toronto, ON, Canada

Fall 2009

Molecular and Cellular Biology for the Physical Scientists

Instructor: Jonathan Rast

University of Toronto, Toronto, ON, Canada

Spring 2009

Optical, Thermal, and Radiation Biophysics

Instructor: Lothar. Lilge

University of Toronto, Toronto, ON, Canada

Spring 2008 

System Optimization

Instructor: Rajni V. Patel                                                   

University of Western Ontario, London, ON, Canada

Fall 2007

Introduction to Medical Imaging

Instructor: Maria Drangova

University of Western Ontario, London, ON, Canada

Spring 2007 

Advanced Image Processing and Analysis

Instructor: Abbas samani

University of Western Ontario, London, ON, Canada

Spring 2007

Finite Element Method

Instructor: Mikko Karttunen

University of Western Ontario, London, ON, Canada

Spring 2006

Machine Vision

Instructor: Babak N. Araabi

University of Tehran, Tehran, Iran

Spring 2006

Digital Signal Processing (DSP)

Instructor: Gholam A. Hossein-Zadeh Dehkordi

University of Tehran, Tehran, Iran

Spring 2006

An Introduction to Biomedical Engineering

Instructor: Seyed Kamaledin Setarehdan

University of Tehran, Tehran, Iran

 

Professional Service

Acted as a reviewer for IEEE Transactions on Medical Imaging (IEEE-TMI), Journal of Magnetic Resonance Imaging (JMRI), Computers in Biology and Medicine (DBM), Canadian Journal of Electrical and Computer Engineering (CJECE), Iranian Journal of Electrical and Computer Engineering (IJECE), Medical Image Computing and Computer Assisted Intervention (MICCAI) and, International Symposium on Biomedical Imaging (ISBI).