Welcome to the Claycomb Lab!

We're working to understand how genes are turned on and off by small RNAs, and how these processes contribute to development and fertility.

In the Claycomb Lab, we are fascinated by all forms of gene regulation by small noncoding RNAs. Our current work aims to uncover the molecular mechanisms by which small RNA pathways modulate chromatin to regulate gene expression, and understand how this regulation impacts development and fertility. We use an integrated experimental approach that includes genetics, genomics, biochemistry and cell and molecular biology. Our mighty champion in this research is the nematode, C. elegans, which has long been an outstanding model system to dissect how small RNAs regulate gene expression.

We're located in the heart of the University of Toronto's St. George Campus.

We're an enthusiastic, hard working group with a passion for understanding the links between epigenetics and fertility. We are always looking for motivated researchers on our team. Sound interesting? Join us!

Stacks Image 1627
Stacks Image 1607
Stacks Image 1609
Stacks Image 1612
Stacks Image 1614
Stacks Image 1617
Stacks Image 1619