John Georgiou_Articles

●2008 Fawcett JP, Georgiou J, Ruston J, Bladt F, Sherman A, Warner N, Saab BJ, Scott R, Roder JC, and Pawson T.
Nck adaptor proteins control the organization of neuronal circuits important for walking.
Proc Natl Acad Sci, 104(52):20973-8.

●2007 Parker JA, Metzler M, Georgiou J, Mage M, Roder JC, Rose AM, Hayden MR, and Néri C.
Huntington-Interacting Protein 1 Influences Worm and Mouse Presynaptic Function and Protects Caenorhabditis elegans Neurons against Mutant Polyglutamine Toxicity.
Journal of Neuroscience, 27(41):11056-64.

●2007 Metzler M, Gan L, Wong TP, Liu L, Helm J, Liu L, Georgiou J, Wang Y, Bissada N, Cheng K, Roder JC, Wang YT, and Hayden MR.
NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1.
Journal of Neuroscience 27(9):2298-2308.

●2005 *Taverna F, *Georgiou J, McDonald RJ, Hong NS, Kraev A, Salter MW, Takeshima H, Muller RU, and Roder JC. Defective place cell activity in nociceptin receptor knockout mice with elevated NMDA receptor-dependent long-term potentiation.
Journal of Physiology 565(Part2):579-591. *Equal contribution

●2004 Georgiou J, Tropak MB, and Roder JC.
Myelin-Associated Glycoprotein Gene.
In: Myelin Biology and Disorders (Vol.1), Lazzarini RA, ed. Academic Press, New York. pp 421-467.
Book Chapter.

●2003 Troncone LRP, Georgiou J, Hua, S-Y, Elrick D, Lebrun I, Magnoli F, and Charlton MP.

Promiscuous and Reversible Blocker of Presynaptic Calcium Channels in Frog and Crayfish Neuromuscular Junctions from Phoneutria nigreventer Spider Venom.
Journal of Neurophysiology 90(5):3529-3537.

**We got the cover photo Sep-Oct 2003; click on photo to enlarge and for caption----->

●2003 Metzler M, Li B, Gan L, Georgiou J, Gutenkunst C-A, Wang Y, Torre E, Devon RS, Oh R, Legendre-Guillemin V, Rich M, Alvarez C, Gertsenstein M, McPherson PS, Nagy A, Wang YT, Roder JC, Raymond LA, and Hayden MR.
Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking.
The EMBO Journal 22(13): 3254-3268.

●1999 Georgiou J and Charlton MP.
Non-myelin forming perisynaptic Schwann cells express protein zero and myelin-associated glycoprotein.
GLIA 27(2):101-109.
***We got the cover photo August 1999; click on photo to enlarge and for caption----->

(0.3 Mb)

●1999 Georgiou J, Robitaille R, and Charlton MP.
Muscarinic control of cytoskeleton in perisynaptic glia.
Journal of Neuroscience 19(10): 3836-3846.

(0.8 Mb)

●1998 Zhou D, Sun AM, Li X, Mamujee SN, Vacek I, Georgiou J, and Wheeler MB.
In vitro and in vivo evaluation of insulin-producing bTC6-F7 cells in microcapsules.
American Journal of Physiology 274(5Pt1):C1356-C1362.

(0.3 Mb)

●1997 Karunanithi S, Georgiou J, Charlton MP and Atwood HL.
Imaging of Calcium in Drosophila Larval Motor Nerve Terminals.
Journal of Neurophysiology 78(6): 3465-7.

(0.4 Mb)

●1997 Atwood HL, Karunanithi S, Georgiou J, and Charlton MP.
Strength and alteration of synaptic transmission at neuromuscular junctions of crustaceans and insects in relation to calcium entry.
Invertebrate Neuroscience 33(2-3):81-87. Review article.

(1.8 Mb)

●1995 Wheeler MB, Gelling RW, McIntosh CH, Georgiou J, Brown JC, and Pederson RA.
Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties.
Endocrinology 136(10):4629-4639.

(1.6 Mb)

●1994 Georgiou J, Robitaille R, Trimble WS, and Charlton MP.
Synaptic regulation of glial protein expression in vivo.
Neuron 12(2): 443-455.

(1.6 Mb)

Below are scientific articles I have published related to neurons and glia at synapses, as well as some non-synaptic work; in the diagram below, colours distinguish each specialization. For each publication, the colour of the circle bullet (beside year) corresponds to the entity which was the primary topic of study. Click on pdf icon to download an article.

Publications: ●2008 Fawcett JP, Georgiou J, Ruston J, Bladt F, Sherman A, Warner N, Saab BJ, Scott R, Roder JC, and Pawson T. Nck adaptor proteins control the organization of neuronal circuits important for walking. *Proc Natl Acad Sci, 104(52):20973-8.* (0.8 Mb) Movie1 (0.7 Mb) Movie2 (1.0 Mb) ●2007 Parker JA, Metzler M, Georgiou J, Mage M, Roder JC, Rose AM, Hayden MR, and Néri C. Huntington-Interacting Protein 1 Influences Worm and Mouse Presynaptic Function and Protects Caenorhabditis elegans Neurons against Mutant Polyglutamine Toxicity. *Journal of Neuroscience, 27(41):11056-64.* (0.8 Mb) ●2007 Metzler M, Gan L, Wong TP, Liu L, Helm J, Liu L, Georgiou J, Wang Y, Bissada N, Cheng K, Roder JC, Wang YT, and Hayden MR. NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1. *Journal of Neuroscience 27(9):2298-2308.* (0.8 Mb) ●2005 Taverna F, Georgiou J, McDonald RJ, Hong NS, Kraev A, Salter MW, Takeshima H, Muller RU, and Roder JC. Defective place cell activity in nociceptin receptor knockout mice with elevated NMDA receptor-dependent long-term potentiation. *Journal of Physiology 565(Part2):579-591.* Equal contribution (0.5 Mb) ●2004 Georgiou J, Tropak MB, and Roder JC. Myelin-Associated Glycoprotein Gene. In: Myelin Biology and Disorders (Vol.1), Lazzarini RA, ed. Academic Press, New York. pp 421-467. Book Chapter.* (1.1 Mb) ●2003 Troncone LRP, Georgiou J, Hua, S-Y, Elrick D, Lebrun I, Magnoli F, and Charlton MP. Promiscuous and Reversible Blocker of Presynaptic Calcium Channels in Frog and Crayfish Neuromuscular Junctions from Phoneutria nigreventer Spider Venom. *Journal of Neurophysiology 90(5):3529-3537. We got the cover photo Sep-Oct 2003; click on photo to enlarge and for caption-----> (0.4 Mb) ●2003 Metzler M, Li B, Gan L, Georgiou J, Gutenkunst C-A, Wang Y, Torre E, Devon RS, Oh R, Legendre-Guillemin V, Rich M, Alvarez C, Gertsenstein M, McPherson PS, Nagy A, Wang YT, Roder JC, Raymond LA, and Hayden MR. Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking. The EMBO Journal 22(13): 3254-3268. (0.5 Mb) ●2001 Henderson JT, Georgiou J, Jia Z, Robertson J, Elowe S, Roder JC and Pawson T. The receptor tyrosine kinase EphB2 regulates NMDA-dependent synaptic function. Neuron 32(6): 1041-1056. (0.9 Mb) ●1999 Georgiou J* and Charlton MP. Non-myelin forming perisynaptic Schwann cells express protein zero and myelin-associated glycoprotein. *GLIA 27(2):101-109. We got the cover photo August 1999; click on photo to enlarge and for caption-----> (0.3 Mb) ●1999 Georgiou J, Robitaille R, and Charlton MP. Muscarinic control of cytoskeleton in perisynaptic glia. Journal of Neuroscience 19(10): 3836-3846. (0.8 Mb) ●1998 Zhou D, Sun AM, Li X, Mamujee SN, Vacek I, Georgiou J, and Wheeler MB. In vitro and in vivo evaluation of insulin-producing bTC6-F7 cells in microcapsules. American Journal of Physiology 274(5Pt1):C1356-C1362. (0.3 Mb) ●1997 Karunanithi S, Georgiou J, Charlton MP and Atwood HL. Imaging of Calcium in Drosophila Larval Motor Nerve Terminals. Journal of Neurophysiology 78(6): 3465-7. (0.4 Mb) ●1997 Atwood HL, Karunanithi S, Georgiou J, and Charlton MP. Strength and alteration of synaptic transmission at neuromuscular junctions of crustaceans and insects in relation to calcium entry. Invertebrate Neuroscience 33(2-3):81-87. Review article. (1.8 Mb) ●1995 Wheeler MB, Gelling RW, McIntosh CH, Georgiou J, Brown JC, and Pederson RA. Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties. Endocrinology 136(10):4629-4639. (1.6 Mb) ●1994 Georgiou J, Robitaille R, Trimble WS, and Charlton MP. Synaptic regulation of glial protein expression in vivo. Neuron 12(2): 443-455**. (1.6 Mb)