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Lab Location
Toronto Western Hospital
McLaughlin Pavillion, Room 9-417
399 Bathurst St.
Toronto, ON, M5T 2S8
Canada

Contact Info

Telephone (Lab): (416)603-5970
Fax: (416)603-5745 (department)
E-mail: schlicht@uhnres.utoronto.ca



Department of Physiology at the University of Toronto University Health Network (UHN)

Copyright © 2010 L.C. Schlichter's Lab. All Rights Reserved.
Webpage designed by Angela Zhou.

Current Projects

Click on the following project titles for more information.

Inflammation and pathology after ischemic or hemorrhagic stroke.

  • Defining the spatial and temporal evolution of inflammation in animal models

  • Assessing the effect of aging on inflammation, damage to neurons and white matter after stroke

  • Molecular/bioinformatic analysis of stroke and hemorrhage in the rat

  • Modifying the outcome of stroke by controlling CNS inflammation

  • Microglial cell functions

  • Defining modes of microglial activation at the molecular level

  • Identifying targets for controlling harmful microglia functions

  • Identifying roles of ion channels in microglial functions

  • Ion channels

  • Expression & biophysical properties: K+, Cl-, TRP, Ca2+, Ca2+-activated K+ channels

  • Modulation of channels by signaling pathways relevant to microglial activation

  • Regulation of channel expression, trafficking and subcellular targeting