Click on the following project titles for more information.
Inflammation and pathology after ischemic or hemorrhagic stroke.
Defining the spatial and temporal evolution of inflammation in animal models
Assessing the effect of aging on inflammation, damage to neurons and white matter after stroke
Molecular/bioinformatic analysis of stroke and hemorrhage in the rat
Modifying the outcome of stroke by controlling CNS inflammation
Microglial cell functions
Defining modes of microglial activation at the molecular level
Identifying targets for controlling harmful microglia functions
Identifying roles of ion channels in microglial functions
Ion channels
Expression & biophysical properties: K+, Cl-, TRP, Ca2+, Ca2+-activated K+ channels
Modulation of channels by signaling pathways relevant to microglial activation
Regulation of channel expression, trafficking and subcellular targeting